Prevalence of Luminal A, Luminal B, HER2 enriched and triple negative breast carcinoma in population of Sindh

The incidence of breast cancer has increased significantly in Asian countries comparison to Western countries, and it is now one the leading causes cancer-related death among women worldwide. Each year, 1.5 million (25% all women) are diagnosed with BC around world, this number expected rise 2.2 by 2025. In particular, shows biologic heterogeneity terms risk factors, natural histories, responses therapy, prognostic features that vary considerably between ethnic geographical groups. Many studies have focused on distinctions tumor subtypes because importance they play guiding therapeutic decision making cancer. These factors include histological grade, type size, presence lymph node metastasis. As a proxy for profiling gene expression, immunohistochemical examination tissue various biomarkers employed. This method cheap, widely accessible, reliable, technically not demanding. purpose research was analyze relationship molecular certain pathological characteristics.